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ABT-737 | ≥99%(HPLC) | Selleck | Bcl-2 阻害剤
ABT-737 | ≥99%(HPLC) | Selleck | Bcl-2 阻害剤

ABT-737 -
ABT-737 -

ABT‑737, a Bcl‑2 family inhibitor, has a synergistic effect with apoptosis  by inducing urothelial carcinoma cell necroptosis
ABT‑737, a Bcl‑2 family inhibitor, has a synergistic effect with apoptosis by inducing urothelial carcinoma cell necroptosis

Apoptosis-based treatment of glioblastomas with ABT-737, a novel small  molecule inhibitor of Bcl-2 family proteins | Oncogene
Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins | Oncogene

ABT-737 promotes tBid mitochondrial accumulation to enhance TRAIL-induced  apoptosis in glioblastoma cells | Cell Death & Disease
ABT-737 promotes tBid mitochondrial accumulation to enhance TRAIL-induced apoptosis in glioblastoma cells | Cell Death & Disease

Bcl-2 is a better ABT-737 target than Bcl-xL or Bcl-w and only Noxa  overcomes resistance mediated by Mcl-1, Bfl-1, or Bcl-B | Cell Death &  Disease
Bcl-2 is a better ABT-737 target than Bcl-xL or Bcl-w and only Noxa overcomes resistance mediated by Mcl-1, Bfl-1, or Bcl-B | Cell Death & Disease

Chemical structure and mode of action of the BH3 mimetic ABT-737 in... |  Download Scientific Diagram
Chemical structure and mode of action of the BH3 mimetic ABT-737 in... | Download Scientific Diagram

ABT-737 reverses the acquired radioresistance of breast cancer cells by  targeting Bcl-2 and Bcl-xL | Journal of Experimental & Clinical Cancer  Research | Full Text
ABT-737 reverses the acquired radioresistance of breast cancer cells by targeting Bcl-2 and Bcl-xL | Journal of Experimental & Clinical Cancer Research | Full Text

ABT-737, an inhibitor of Bcl-2 family proteins, is a potent inducer of  apoptosis in multiple myeloma cells | Leukemia
ABT-737, an inhibitor of Bcl-2 family proteins, is a potent inducer of apoptosis in multiple myeloma cells | Leukemia

Bcl-2 is a better ABT-737 target than Bcl-xL or Bcl-w and only Noxa  overcomes resistance mediated by Mcl-1, Bfl-1, or Bcl-B | Cell Death &  Disease
Bcl-2 is a better ABT-737 target than Bcl-xL or Bcl-w and only Noxa overcomes resistance mediated by Mcl-1, Bfl-1, or Bcl-B | Cell Death & Disease

PROTACs are effective in addressing the platelet toxicity associated with  BCL-XL inhibitors
PROTACs are effective in addressing the platelet toxicity associated with BCL-XL inhibitors

Frontiers | BH3 Mimetics for the Treatment of Prostate Cancer
Frontiers | BH3 Mimetics for the Treatment of Prostate Cancer

IJMS | Free Full-Text | BCL-2 Inhibitor ABT-737 Effectively Targets  Leukemia-Initiating Cells with Differential Regulation of Relevant Genes  Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High  Risk-Myelodysplastic Syndrome
IJMS | Free Full-Text | BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome

Chemical structures of ABT-737 (left) and ABT-263 (right ). | Download  Scientific Diagram
Chemical structures of ABT-737 (left) and ABT-263 (right ). | Download Scientific Diagram

Ionizing Radiation Sensitizes Breast Cancer Cells to Bcl-2 Inhibitor, ABT- 737, through Regulating Mcl-1
Ionizing Radiation Sensitizes Breast Cancer Cells to Bcl-2 Inhibitor, ABT- 737, through Regulating Mcl-1

Bcl-2 is a better ABT-737 target than Bcl-xL or Bcl-w and only Noxa  overcomes resistance mediated by Mcl-1, Bfl-1, or Bcl-B – topic of research  paper in Biological sciences. Download scholarly article
Bcl-2 is a better ABT-737 target than Bcl-xL or Bcl-w and only Noxa overcomes resistance mediated by Mcl-1, Bfl-1, or Bcl-B – topic of research paper in Biological sciences. Download scholarly article

ABT-737 is a Selective and BH3 Mimetic Bcl-2, Bcl-xL and Bcl-w Inhibitor -  Network of Cancer Research
ABT-737 is a Selective and BH3 Mimetic Bcl-2, Bcl-xL and Bcl-w Inhibitor - Network of Cancer Research

Combined treatment with ABT-737 and VX-680 induces apoptosis in Bcl-2- and  c-FLIP-overexpressing breast carcinoma cells
Combined treatment with ABT-737 and VX-680 induces apoptosis in Bcl-2- and c-FLIP-overexpressing breast carcinoma cells

ABT-737 - Wikipedia
ABT-737 - Wikipedia

Cancers | Free Full-Text | The Application of Arsenic Trioxide in  Ameliorating ABT-737 Target Therapy on Uterine Cervical Cancer Cells  through Unique Pathways in Cell Death
Cancers | Free Full-Text | The Application of Arsenic Trioxide in Ameliorating ABT-737 Target Therapy on Uterine Cervical Cancer Cells through Unique Pathways in Cell Death

ABT-737 overcomes Bcl-2 mediated resistance to doxorubicin–DNA adducts -  ScienceDirect
ABT-737 overcomes Bcl-2 mediated resistance to doxorubicin–DNA adducts - ScienceDirect

ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases  antimitotic-mediated apoptosis in human prostate cancer cells [PeerJ]
ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases antimitotic-mediated apoptosis in human prostate cancer cells [PeerJ]

Schematic summary of the effects of ABT-737 on human oral cancer cells....  | Download Scientific Diagram
Schematic summary of the effects of ABT-737 on human oral cancer cells.... | Download Scientific Diagram

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently  induces apoptosis via Bak/Bax if Mcl-1 is neutralized - ScienceDirect
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized - ScienceDirect

PDF] Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic  ABT-737 in acute myeloid leukemia. | Semantic Scholar
PDF] Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia. | Semantic Scholar

ABT-737 affected cell growth, induced apoptosis and modulated Bcl-2... |  Download Scientific Diagram
ABT-737 affected cell growth, induced apoptosis and modulated Bcl-2... | Download Scientific Diagram